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Prioritizing Symptoms of ESRD Patients for Developing Therapeutic Interventions

Kidney Health Initiative logoThe Kidney Health Initiative, a public-private partnership between the American Society of Nephrology (ASN) and the US Food and Drug Administration (FDA), recently completed a project that prioritized symptoms experienced by patients on dialysis.The workgroup identified near term, actionable research goals for the nephrology community to develop innovative therapies to alleviate these symptoms.

This project was co-chaired by Jennifer E. Flythe, MD, MPH, FASN, from the University of North Carolina Kidney Center, and Rajnish Mehrotra, MD, FASN, from the University of Washington.

Despite the priority that patients put on alleviating symptoms from dialysis treatment, there has been little research into improving patient symptoms and minimal innovation in managing these symptoms. This project provides patient preferences and pathophysiology information for innovators and researchers to foster development of new therapies. 

Publications from the project:

Symptom Prioritization among Adults Receiving In-Center Hemodialysis
Jennifer E. Flythe, Tandrea Hilliard, Graciela Castillo, Kourtney Ikeler, Jazmine Orazi, Emaad Abdel-Rahman, Amy Barton Pai, Matthew B. Rivara, Wendy L. St. Peter, Steven D. Weisbord, Caroline Wilkie, Rajnish Mehrotra
CJASN May 2018, 13 (5) 735-745; DOI: 10.2215/CJN.10850917

Fostering Innovation in Symptom Management among Hemodialysis Patients
Jennifer E. Flythe, Tandrea Hilliard, Elena Lumby, Graciela Castillo, Jazmine Orazi, Emaad M. Abdel-Rahman, Amy Barton Pai, Matthew B. Rivara, Wendy L. St. Peter, Steven Darrow Weisbord, Caroline M. Wilkie, Rajnish Mehrotra, for the Kidney Health Initiative Prioritizing Symptoms of ESRD Patients for Developing Therapeutic Interventions Stakeholder Meeting Participants
CJASN Nov 2018, CJN.07670618; DOI: 10.2215/CJN.07670618

Learn more about the Kidney Health Initiative (KHI)