Research broadens the knowledge of kidney disease.

Select research articles from our Nephrology faculty. For a full list of articles, see the sidebar and click on a faculty name.

Recurrent glomerular disease after kidney transplantation

Blosser CD, Bloom RD

Gene-Edited Human Kidney Organoids Reveal Mechanisms of Disease in Podocyte Development

Kim YK, Refaeli I, Brooks CR, Jing P, Gulieva RE, Hughes MR, Cruz NM, Liu Y, Churchill AJ, Wang Y, Fu H, Pippin JW, Lin LY, Shankland S, Vogl AW, McNagny KM, Freedman BS

Organoid cystogenesis reveals a critical role of microenvironment in human polycystic kidney disease

Cruz NM, Song X, Czerniecki SM, Gulieva RE, Churchill AJ, Kim YK, Winston K, Tran LM, Diaz MA, Fu H, Finn LS, Pei Y, Himmelfarb JFreedman BS

Circulating levels of soluble Fas (sCD95) are associated with risk for development of a nonresolving acute kidney injury subphenotype

Bhatraju PK, Robinson-Cohen C, Mikacenic C, Harju-Baker S, Dmyterko V, Slivinski NSJ, Liles WC, Himmelfarb J, Heckbert SR, Wurfel MM

Non-GFR Determinants of Low-Molecular-Weight Serum Protein Filtration Markers in the Elderly: AGES-Kidney and MESA-Kidney

Foster MC, Levey AS, Inker LA, Shafi T, Fan L, Gudnason V, Katz R, Mitchell GF, Okparavero A, Palsson R, Post WS, Shlipak MG

Development of a microphysiological model of human kidney proximal tubule function

Weber EJ, Chapron A, Chapron BD, Voellinger JL, Lidberg KA, Yeung CK, Wang Z, Yamaura Y, Hailey DW, Neumann T, Shen DD, Thummel KE, Muczynski KAHimmelfarb J, Kelly EJ.

Coloduodenovesical Fistula After Simultaneous Pancreas-Kidney Transplant: Case Report and Review of the Literature

Rahnemai-Azar AA, Penna M, Morrison SD, Rayhill SC, Sibulesky L, Muczynski KA, Bakthavatsalam R

Making Sense of Prognostic Information About Maintenance Dialysis versus Conservative Care for Treatment of Advanced Kidney Disease

Wong S.P.Y.O'Hare A.M.

Embracing Complexity: How to Build an Evidence Base Capable of Supporting Patient-Centered Care

Physical Activity Dose for Hemodialysis Patients: Where to Begin? Results from a Prospective Cohort Study

Matsuzawa R, Roshanravan B, Shimoda T, Mamorita N, Yoneki K, Harada M, Watanabe T, Yoshida A, Takeuchi Y, Matsunaga A.

WT1 Is Necessary for the Proliferation and Migration of Cells of Renin Lineage Following Kidney Podocyte Depletion

Kaverina NV, Eng DG, Largent AD, Daehn I, Chang A, Gross KW, Pippin JW, Hohenstein P, Shankland SJ

Association of Serum Amyloid A with Kidney Outcomes and All-Cause Mortality in American Indians with Type 2 Diabetes

Saulnier PJ, Dieter BP, Tanamas SK, McPherson SM, Wheelock KM, Knowler WC, Looker HC, Meek RL, Nelson RG, Tuttle KR

Chronic kidney disease and incident apparent treatment-resistant hypertension among blacks: Data from the Jackson Heart Study

Tanner RM, Shimbo D, Irvin MR, Spruill TM, Bromfield SG, Seals SR, Young BA, Muntner P

A New Chapter for Diabetic Kidney Disease

Ian H. de Boer

Diabetes and Hypertension: A Position Statement by the American Diabetes Association

Ian H. de Boer, Sripal Bangalore, Athanase Benetos, Andrew M. Davis, Erin D. Michos, Paul Muntner, Peter Rossing, Sophia Zoungas, George Bakris

eGFR and Albuminuria in Relation to Risk of Incident Atrial Fibrillation: A Meta-Analysis of the Jackson Heart Study, the Multi-Ethnic Study of Atherosclerosis, and the Cardiovascular Health Study

Nisha BansalLeila R. Zelnick, Alvaro Alonso, Emelia J. Benjamin, Ian H. de Boer, Rajat Deo‖, Ronit Katz, Bryan Kestenbaum, Jehu Mathew, Cassianne Robinson-Cohen, Mark J. Sarnak, Michael G. Shlipak, Nona Sotoodehnia, Bessie Young, Susan R. Heckbert

Tuegel C, Bansal N

Blood Pressure and Risk of Cardiovascular Events in Patients on Chronic Hemodialysis: The CRIC Study (Chronic Renal Insufficiency Cohort)

Bansal N, McCulloch CE, Lin F, Alper A, Anderson AH, Cuevas M, Go AS, Kallem R, Kusek JW, Lora CM, Lustigova E, Ojo A, Rahman M, Robinson-Cohen C, Townsend RR, Wright J, Xie D, Hsu CY; CRIC Study Investigators

Kidney function is associated with an altered protein composition of high-density lipoprotein

Rubinow KB, Henderson CM, Robinson-Cohen C, Himmelfarb Jde Boer IH, Vaisar T, Kestenbaum B, Hoofnagle AN

Identification, Confirmation, and Replication of Novel Urinary MicroRNA Biomarkers in Lupus Nephritis and Diabetic Nephropathy

Cardenas-Gonzalez M, Srivastava A, Pavkovic M, Bijol V, Rennke HG, Stillman IE, Zhang X, Parikh S, Rovin BH, Afkarian M, de Boer IHHimmelfarb J, Waikar SS, Vaidya VS

Relation of Serum Vitamin D to Risk of Mitral Annular and Aortic Valve Calcium (from the Multi-Ethnic Study of Atherosclerosis)

Tibuakuu M, Zhao D, de Boer IH, Guallar E, Bortnick AE, Lutsey PL, Budoff MJ, Kizer JR, Kestenbaum BR, Michos ED

Effects of Vitamin D2 Supplementation on Vitamin D3 Metabolism in Health and CKD

Batacchi Z, Robinson-Cohen C, Hoofnagle AN, Isakova T, Kestenbaum B, Martin KJ, Wolf MS, de Boer IH

Does Secretory Clearance Follow Glomerular Filtration Rate in Chronic Kidney Diseases? Reconsidering the Intact Nephron Hypothesis

Chapron A, Shen DD, Kestenbaum BR, Robinson-Cohen C, Himmelfarb J, Yeung CK

Standardized outcomes in nephrolgoy-peritoneal dialysis (SONG-PD): Study protocol for establishing a core outcome set in PD

Manera KE, Tong A, Craig JC, Brown EA, Brunier G, Dong J, Dunning T, Mehrotra R, Naicker S, Pecoits-Filho R, Perl J, Wang AY, Wilkie M, Howell M, Sautenet B, Evangelidis N, Shen JI, Johnson DW

Rivara MBMehrotra R

Retinoic acid improves nephrotoxic serum-induced glomerulonephritis through activation of podocyte retinoic acid receptor α

Dai Y, Chen A, Liu R, Gu L, Sharma S, Cai W, Salem F, Salant DJ, Pippin JW, Shankland SJ, Moeller MJ, Ghyselinck NB, Ding X, Chuang PY, Lee K, He JC

Association between Endothelin-1 Levels and Kidney Disease among Blacks

Rebholz CM, Harman JL, Grams ME, Correa A, Shimbo D, Coresh J, Young BA

Associations of Vitamin D-Binding Globulin and Bioavailable Vitamin D Concentrations with Coronary Heart Disease Events: The Multi-Ethnic Study of Atherosclerosis (MESA)

Robinson-Cohen C, Zelnick LR, Hoofnagle AN, Lutsey PL, Burke G, Michos ED Shea SJC, Tracy R, Siscovick DS, Psaty B, Kestenbaum Bde Boer IH

Nephrotic syndrome in pregnancy poses risks with both maternal and fetal complications

De Castro I, Easterling TR, Bansal NJefferson JA

Persistent Gaps in Use of Advance Directives Among Nursing Home Residents Receiving Maintenance Dialysis

Kurella Tamura M, Liu S, Montez-Rath ME, O'Hare AMHall YN, Lorenz KA

Comparison between Different Measures of Body Fat with Kidney Function Decline and Incident CKD

Madero M, Katz R, Murphy R, Newman A, Patel K, Ix J, Peralta C, Satterfield S, Fried L, Shlipak M, Sarnak M

Repression of Interstitial Identity in Nephron Progenitor Cells by Pax2 Establishes the Nephron-Interstitium Boundary during Kidney Development

Natalie Naiman, Kaoru Fujioka, Mari Fujino, M. Todd Valerius, S. Steven Potter, Andrew P. McMahon, Akio Kobayashi

Sex Differences in Hospitalizations with Maintenance Hemodialysis

Adams SV, Rivara M, Streja E, Cheung AK, Arah OA, Kalantar-Zadeh K, Mehrotra R

Choice of Hemodialysis Access in Older Adults: A Cost-Effectiveness Analysis

Hall RK, Myers ER, Rosas SE, O'Hare AM, Colón-Emeric CS

Targeting Access to Kidney Care Via Telehealth: The VA Experience

Crowley ST, Belcher J, Choudhury D, Griffin C, Pichler R, Robey B, Rohatgi R, Mielcarek B

Exercise and CKD: Skeletal Muscle Dysfunction and Practical Application of Exercise to Prevent and Treat Physical Impairments in CKD

Roshanravan B, Gamboa J, Wilund K

The mitochondrial-targeted peptide, SS-31, improves glomerular architecture in mice of advanced age

Sweetwyne MT, Pippin JW, Eng DG, Hudkins KL, Chiao YA, Campbell MD, Marcinek DJ, Alpers CE, Szeto HH, Rabinovitch PS, Shankland SJ

 

Diabetic Kidney Disease: Challenges, Progress, and Possibilities

Alicic RZ, Rooney MT, Tuttle KR

Factors associated with maintenance of body mass index in the Jackson Heart Study: A prospective cohort study secondary analysis

Auerbach BJ, Katz R, Tucker K, Boyko EJ, Drewnowski A, Bertoni A, Dubbert P, Hickson DA, Correa A, Young BA

The kidney's role in systemic metabolism - still much to learn

de Boer IH, Utzschneider KM

Maternal obesity is associated with congenital anomalies of the kidney and urinary tract in offspring

Macumber I, Schwartz S, Leca N

Introduction to 30 Years: Lessons Learned in Dialysis

Nissenson AR, Mehrotra R

Repression of Interstitial Identity in Nephron Progenitor Cells by Pax2 Establishes the Nephron-Interstitium Boundary during Kidney Development

Natalie Naiman, Kaoru Fujioka, Mari Fujino, M. Todd Valerius, S. Steven Potter, Andrew P. McMahon, Akio Kobayashi

The Evolution of Cardiovascular Disease During the Transition to End-Stage Renal Disease

Bansal N

Can podocytes be regenerated in adults?

Shankland, Stuart J., Freedman, Benjamin S., Pippin, Jeffrey W.

Tracking the stochastic fate of cells of the renin lineage after podocyte depletion using multicolor reporters and intravital imaging

Natalya V. Kaverina, Hiroyuki Kadoya, Diana G. Eng,Michael E. Rusiniak, Maria Luisa S. Sequeira-Lopez, R. Ariel Gomez, Jeffrey W. Pippin, Kenneth W. Gross, Janos Peti-Peterdi, Stuart J. Shankland

Factors associated with maintenance of body mass index in the Jackson Heart Study: A prospective cohort study secondary analysis

Brandon J. Auerbach, Ronit Katz, Katherine Tucker, Edward J. Boykoa, Adam Drewnowskie, Alain Bertonif, Patricia Dubbertg, DeMarc A. Hicksonh, Adolfo Correai, Bessie A. Young

A bone marrow factor contributes to kidney disease

Stuart J ShanklandJ Ashley Jefferson

Genetic Variants Associated with Circulating Parathyroid Hormone

Cassianne Robinson-Cohen, Bryan Kestenbaum

Effect of Coenzyme Q10 on Biomarkers of Oxidative Stress and Cardiac Function in Hemodialysis Patients: The CoQ10 Biomarker Trial

Matthew B. Rivara, Catherine K. Yeung, Cassianne Robinson-Cohen, Brian R. Phillips, John Ruzinski, Denise Rock, Lori Linke, Danny D. Shen, T. Alp Ikizler, Jonathan Himmelfarb

Association of Muscle Endurance, Fatigability, and Strength With Functional Limitation and Mortality in the Health Aging and Body Composition Study

Baback Roshanravan, Kushang V. Patel, Linda F. Fried, Cassianne Robinson-Cohen, Ian H. de Boer, Tamara Harris, Rachel A. Murphy, Suzanne Satterfield, Bret H. Goodpaster, Michael Shlipak, Anne B. Newman, Bryan Kestenbaum

Albuminuria Changes and Cardiovascular and Renal Outcomes in Type 1 Diabetes: The DCCT/EDIC Study

Ian H. de Boer, Xiaoyu Gao, Patricia A. Cleary, Ionut Bebu, John M. Lachin, Mark E. Molitch, Trevor Orchard, Andrew D. Paterson, Bruce A. Perkins, Michael W. Steffes, Bernard Zinman

The Current State of Peritoneal Dialysis

Mehrotra R, Devuyst O, Davies SJ, Johnson DW

CKD and Muscle Mitochondrial Energetics

Baback Roshanravan, Bryan Kestenbaum, Jorge Gamboa, Sharon A. Jubrias, Ernest Ayers, Laura Curtin, Jonathan Himmelfarb, Ian. H. de Boer, Kevin E. Conley 

Partial podocyte replenishment in experimental FSGS derives from nonpodocyte sources.

Kaverina NV, Eng DG, Schneider RR, Pippin JW, Shankland SJ

Impaired Glucose and Insulin Homeostasis in Moderate-Severe CKD

Ian H. de Boer, Leila Zelnick, Maryam Afkarian, Ernest Ayers, Laura Curtin, Jonathan Himmelfarb, T. Alp Ikizler, Steven E. Kahn, Bryan Kestenbaum, Kristina Utzschneider

Cells of renin lineage express hypoxia inducible factor 2α following experimental ureteral obstruction

Ania Stefanska, Diana Eng, Natalya Kaverina, Jeffrey W. Pippin, Kenneth W. Gross, Jeremy S. Duffield, Stuart J. Shankland

Eculizumab use in kidney transplantation

Johnson CK, Leca N

Risk Factors for Rapid Kidney Function Decline Among African Americans: The Jackson Heart Study (JHS)

Young BA, Katz R, Boulware LE, Kestenbaum B, de Boer IH, Wang W, Fülöp T, Bansal N, Robinson-Cohen C, Griswold M, Powe NN, Himmelfarb J, Correa A

The Evolving Ethics of Dialysis in the United States: A Principlist Bioethics Approach

Catherine R. Butler, Rajnish Mehrotra, Mark R. Tonelli, Daniel Y. Lam